[Immunohistochemistry characterization of neurocytoma of the cerebral hemispheres]

Arkh Patol. 1997 Jan-Feb;59(1):51-7.
[Article in Russian]

Abstract

Neurocytoma accounts for 0.5% of all tumors of the central nervous system. 18 such tumors are described. Homogeneous expression of neuron-specific enolase and synaptophysin and heterogeneous expression of PCNA and some proteins are characteristic for these tumors. Two immunophenotypic variants are distinguished: p30-32 positive tumors with high values of PCNA; c-er B-2 HSPh-highly positive variant with lower indices of the "growth fractions".

Publication types

  • Clinical Trial
  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Antigens, Neoplasm / analysis*
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / immunology*
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunohistochemistry
  • Immunophenotyping
  • Infant
  • Male
  • Middle Aged
  • Neurocytoma / diagnosis
  • Neurocytoma / immunology*
  • Phosphopyruvate Hydratase / analysis*
  • Proliferating Cell Nuclear Antigen / analysis*
  • Synaptophysin / analysis

Substances

  • Antigens, Neoplasm
  • Proliferating Cell Nuclear Antigen
  • Synaptophysin
  • Phosphopyruvate Hydratase