Abstract
Although pyoctanin is widely used in medicine, there are hardly any reports of contact allergy to it. Most reports of side-effects refer to irritant reactions after topical application. We describe 2 patients who developed pyoctanin contact dermatitis after long-term application on damaged skin. Positive patch test results down to concentrations of 0.0025% and 0.05% aqueous pyoctanin solution, respectively, were found.
MeSH terms
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Administration, Topical
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Adrenal Cortex Hormones / therapeutic use
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Anti-Infective Agents, Local / administration & dosage
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Anti-Infective Agents, Local / adverse effects*
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Anti-Infective Agents, Local / therapeutic use
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Dermatitis, Allergic Contact / diagnosis
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Dermatitis, Allergic Contact / drug therapy
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Dermatitis, Allergic Contact / etiology*
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Foot Dermatoses / diagnosis
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Foot Dermatoses / drug therapy
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Gentian Violet / administration & dosage
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Gentian Violet / adverse effects*
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Gentian Violet / therapeutic use
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Humans
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Leg Dermatoses / diagnosis
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Leg Dermatoses / drug therapy
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Male
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Middle Aged
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Skin Diseases, Papulosquamous / diagnosis
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Skin Diseases, Papulosquamous / drug therapy
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Tinea Pedis / diagnosis
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Tinea Pedis / drug therapy
Substances
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Adrenal Cortex Hormones
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Anti-Infective Agents, Local
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Gentian Violet