A series of 17 cases of congenital cystic adenomatoid malformation of the lung: management and outcome

Eur J Pediatr Surg. 1997 Apr;7(2):84-9. doi: 10.1055/s-2008-1071060.

Abstract

During a 5-year-period, 17 cases of congenital adenomatoid malformation of the lung were observed in the Department of Pediatric Surgery of Bologna University-S. Orsola-Malpighi Hospital; 16 cases were diagnosed in utero by ultra-sound. 13 patients had prenatal diagnosis between 21 and 23 weeks of gestation; 2 cases were diagnosed at 25 weeks and another one at 26 weeks. The other case came from another hospital, and the diagnosis was accidentally detected postnatally. In 3 cases the parents decided to terminate the pregnancy 3 cases had spontaneous improvement during the last weeks of gestation, and were perfectly normal at birth. One case was lost to follow-up; all remaining patients underwent resection. Among these patients only one was a nonsurvivor, while 9 have completely recovered. However, one patient developed persistent pulmonary hypertension, which could successfully be treated with drugs, another underwent laser treatment for laryngeal stenosis due to intubation. A special epidemiological information: 13 out 17 cases (76.5%) were female.

MeSH terms

  • Cystic Adenomatoid Malformation of Lung, Congenital / complications
  • Cystic Adenomatoid Malformation of Lung, Congenital / diagnosis
  • Cystic Adenomatoid Malformation of Lung, Congenital / surgery*
  • Female
  • Humans
  • Hypertension, Pulmonary / etiology
  • Infant
  • Laser Therapy
  • Male
  • Pregnancy
  • Prenatal Diagnosis
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Ultrasonography