Mechanisms of immunity to the respiratory pathogen Bordetella pertussis in normal and gene knockout mice: clearance of primary infection is not enhanced by therapeutic interleukin-12

Biochem Soc Trans. 1997 May;25(2):341S. doi: 10.1042/bst025341s.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aerosols
  • Animals
  • Bordetella pertussis / immunology*
  • Injections, Intraperitoneal
  • Interferon gamma Receptor
  • Interleukin-12 / administration & dosage
  • Interleukin-12 / therapeutic use*
  • Lung / immunology
  • Mice
  • Mice, Inbred BALB C
  • Mice, Knockout
  • Receptors, Interferon / deficiency
  • Receptors, Interferon / genetics
  • Receptors, Interferon / physiology*
  • Recombinant Proteins / administration & dosage
  • Recombinant Proteins / therapeutic use
  • Reference Values
  • Th1 Cells / immunology
  • Th2 Cells / immunology
  • Whooping Cough / immunology*
  • Whooping Cough / prevention & control
  • Whooping Cough / therapy

Substances

  • Aerosols
  • Receptors, Interferon
  • Recombinant Proteins
  • Interleukin-12