Disappearance of the 'no-reflow' phenomenon after adjunctive intracoronary administration of nicorandil in a patient with acute myocardial infarction

Y Sakata; K Kodama; F Ishikura; K Komamura; S Hasegawa; Y Sakata; A Hirayama

doi:10.1253/jcj.61.455

Disappearance of the 'no-reflow' phenomenon after adjunctive intracoronary administration of nicorandil in a patient with acute myocardial infarction

Jpn Circ J. 1997 May;61(5):455-8. doi: 10.1253/jcj.61.455.

Authors

Y Sakata¹, K Kodama, F Ishikura, K Komamura, S Hasegawa, Y Sakata, A Hirayama

Affiliation

¹ Cardiovascular Division, Osaka Police Hospital, Japan.

PMID: 9192246
DOI: 10.1253/jcj.61.455

Abstract

Adjunctive intracoronary administration of nicorandil, an ATP-sensitive potassium channel opener, after successful coronary revascularization was performed in a 54-year-old patient with acute myocardial infarction. The 'no-reflow' phenomenon disappeared after nicorandil administration and significant functional recovery of the infarcted myocardium was achieved. This suggests that nicorandil could eliminate the 'no-reflow' phenomenon after successful coronary revascularization.

Publication types

Case Reports

MeSH terms

Coronary Circulation / drug effects*
Coronary Vessels
Humans
Injections
Male
Middle Aged
Myocardial Infarction / diagnostic imaging
Myocardial Infarction / drug therapy*
Myocardial Infarction / physiopathology
Myocardial Reperfusion
Niacinamide / administration & dosage
Niacinamide / analogs & derivatives*
Niacinamide / therapeutic use
Nicorandil
Potassium Channels / agonists*
Thrombolytic Therapy
Ultrasonography

Substances

Potassium Channels
Niacinamide
Nicorandil