Abstract
The local slow release of an anticancer agent by one route is a form of treatment. There have been numerous reports to date that this approach might be a promising adjuvant for systemic therapy. We investigated the spraying of the operative field at a local site with cisplatin, which is considered the most effective carcinostatic in the field of lung cancer, and reported it in clinical cases selected in applying a Pilot-Study. The feature of this method is to use fibrin to spray drugs uniformly over a wide field. We expect it will be an adjuvant for postoperative purification and other uses.
MeSH terms
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Adenocarcinoma / drug therapy
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Adenocarcinoma / surgery
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Adult
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Aerosols
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Aged
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
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Carboplatin / administration & dosage
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Carcinoma, Squamous Cell / drug therapy
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Carcinoma, Squamous Cell / surgery
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Cisplatin / administration & dosage*
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Combined Modality Therapy
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Female
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Fibrin Tissue Adhesive / administration & dosage
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Humans
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Intraoperative Care
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Lung Neoplasms / drug therapy*
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Lung Neoplasms / surgery
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Male
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Middle Aged
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Nebulizers and Vaporizers
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Vindesine / administration & dosage
Substances
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Aerosols
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Fibrin Tissue Adhesive
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Carboplatin
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Cisplatin
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Vindesine