Abstract
In systemic lupus erythematosus (SLE), the central nervous system (CNS) produces numerous and varying clinical disorders. A 14-year-old girl with the features of cerebral involvement in SLE is presented. The development of diabetes insipidus (DI), which responded to desmopressin, was an interesting finding in this case. Therapy consisting of high-dose methylprednisolone combined with cyclophosphamide was effective in improving the symptoms as well as the DI.
MeSH terms
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Adolescent
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Anti-Inflammatory Agents / therapeutic use
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Cyclophosphamide / therapeutic use
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Deamino Arginine Vasopressin / therapeutic use
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Diabetes Insipidus / drug therapy
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Diabetes Insipidus / etiology*
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Drug Therapy, Combination
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Female
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Humans
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Hypoglycemic Agents / therapeutic use
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Immunosuppressive Agents / therapeutic use
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Lupus Erythematosus, Systemic / complications*
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Methylprednisolone / therapeutic use
Substances
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Anti-Inflammatory Agents
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Hypoglycemic Agents
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Immunosuppressive Agents
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Cyclophosphamide
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Deamino Arginine Vasopressin
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Methylprednisolone