Study objective: To evaluate a new method of outpatient hysteroscopy.
Design: Prospective observational study.
Setting: Departments of Obstetrics and Gynecology, Medical School of Ioannina, Greece, and Brooklyn Hospital Center, Brooklyn, New York.
Patients: Three hundred twenty-four women, 316 of whom were symptomatic and 8 asymptomatic.
Interventions: Hysteroscopic vaginoscopy with directed endometrial biopsies.
Measurements and main results: The procedure was successful and well tolerated in 211 (65%) women. In 90 (27.9%) women, the procedure was successful but with significant pelvic pain, and in the remaining 23 (7.1%) it was complicated by either vagal reaction or complete intolerance. Hysteroscopic findings were in agreement with histopathologic results in 290 (89.5%) patients. In all 12 women with endometrial adenocarcinoma, hysteroscopic findings were identical with histopathologic results.
Conclusion: The vaginoscopic approach is effective for outpatient hysteroscopy.