Type-4 pili of Kingella denitrificans

Gene. 1997 Jun 11;192(1):171-6. doi: 10.1016/s0378-1119(96)00828-1.

Abstract

Kingella denitrificans possess type-4 pili, and the type strain, ATCC 33394, contains at least four complete copies of type-4 pilin-encoding genes. Previously reported hybridization patterns of K. denitrificans chromosomal DNA seen using a Neisseria gonorrhoeae pilin gene region probe, had been interpreted as representing possible partial, silent gene loci. This now appears to be due to cross-reaction to multiple copies of 18-bp inverted repeat structures. Data are presented on a variety of colony variants which have changed from a spreading-corroding (SC) phenotype to a nonspreading-noncorroding (N) phenotype. Interestingly, while the SC to N transition is most often associated with loss of piliation in other bacteria containing type-4 pili, many of the K. denitrificans N variants still produce pilin, and some still produce pili.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bacterial Outer Membrane Proteins / genetics*
  • Blotting, Southern
  • Blotting, Western
  • DNA Probes
  • Fimbriae Proteins
  • Fimbriae, Bacterial / chemistry*
  • Fimbriae, Bacterial / genetics
  • Gene Dosage
  • Gene Expression Regulation, Bacterial
  • Genes, Bacterial*
  • Kingella / chemistry*
  • Kingella / genetics
  • Kingella / pathogenicity
  • Microscopy, Electron
  • Phenotype

Substances

  • Bacterial Outer Membrane Proteins
  • DNA Probes
  • Fimbriae Proteins