Incidental appendix carcinoid. Value of somatostatin receptor imaging

Clin Nucl Med. 1997 Jul;22(7):467-9. doi: 10.1097/00003072-199707000-00004.

Abstract

Purpose: Somatostatin receptor scintigraphy is used to diagnose carcinoid of the gastrointestinal tract. Its sensitivity ranges from approximately 75%-100%. Therefore, it was hypothesized that it can be used in the postsurgical follow-up to detect residual carcinoid, recurrence, and metastatic disease.

Results: This article is concerned with the findings of somatostatin receptor imaging performed on a 12-year-old girl 8 weeks after appendectomy. Histologic examination showed an incidental appendix carcinoid. Somatostatin receptor scintigraphy performed for detection of lymph node metastatic spread of the carcinoid showed focal tracer accumulation at the former operative site; subsequently, a right hemicolectomy was performed. However, histologic examination of the surgical tissue showed no evidence for carcinoid.

Conclusion: It is concluded that there are some potential pitfalls for somatostatin receptor imaging at least soon after surgery. Therefore, it should not be used to aid in reoperation.

Publication types

  • Case Reports

MeSH terms

  • Appendiceal Neoplasms / diagnostic imaging*
  • Appendiceal Neoplasms / metabolism
  • Appendiceal Neoplasms / secondary
  • Appendiceal Neoplasms / surgery
  • Carcinoid Tumor / diagnostic imaging*
  • Carcinoid Tumor / metabolism
  • Carcinoid Tumor / surgery
  • Child
  • Female
  • Humans
  • Indium Radioisotopes*
  • Lymphatic Metastasis
  • Neoplasm, Residual
  • Octreotide / analogs & derivatives*
  • Pentetic Acid / analogs & derivatives*
  • Radionuclide Imaging
  • Radiopharmaceuticals*
  • Receptors, Somatostatin / analysis*

Substances

  • Indium Radioisotopes
  • Radiopharmaceuticals
  • Receptors, Somatostatin
  • SDZ 215-811
  • Pentetic Acid
  • Octreotide