A high-speed gated baseline restorer and its implementation in a blood cell volume analyser

Med Eng Phys. 1997 Apr;19(3):267-72. doi: 10.1016/s1350-4533(96)00061-6.

Abstract

Accurate measurement of the height of individual pulses in a signal that is a.c.-coupled is dependent upon correcting a changing baseline to a constant value. A new fast baseline restorer, using internally triggered gated feedback with gain, has been designed and a version optimized for Gaussian-shaped pulses. Performance is dependent on the magnitudes of both the forward and the feedback gains. The design presented can achieve a 0.5% accuracy in pulse height for a minimum pulse width of 2.5 microseconds or for 5 microseconds overlapping pulses as long as the overlap is less than 50%. Typical applications for the baseline restorer include blood cell volume measurement systems, scintillation counters and radiation spectroscopy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomedical Engineering
  • Blood Cells / cytology*
  • Cell Size
  • Electronics, Medical
  • Equipment Design
  • Evaluation Studies as Topic
  • Feedback
  • Flow Cytometry / instrumentation*
  • Humans