[Latent long QT syndrome: discription of a clinical case]

G Ital Cardiol. 1997 Apr;27(4):374-9.
[Article in Italian]

Abstract

Latent forms of long QT syndrome have been already reported. We describe one case of a 27 years old female patient who experienced an episode of cardiac arrest after several puffs of salbutamole. The malignant arrhythmia causing the cardiac arrest was torsade de pointes degenerated into ventricular fibrillation. The patient ECG showed a normal QTc basal interval and the correct diagnosis was made by contemporary recording of the ECG and MAP during orciprenalina infusion. After drug infusion, we have recorded a MAP lengthening and a dispersion of MAP duration between the right ventricular apex and the right ventricular outflow tract. These modifications were concomitant with the appearance of "humps" (probably related to the presence of early afterdepolarizations), a QT interval lengthening and morphologic changes of the T and U waves.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Administration, Inhalation
  • Adrenergic beta-Agonists / administration & dosage
  • Adrenergic beta-Agonists / adverse effects
  • Adrenergic beta-Agonists / pharmacology
  • Adrenergic beta-Agonists / therapeutic use
  • Adult
  • Albuterol / administration & dosage
  • Albuterol / adverse effects
  • Albuterol / therapeutic use
  • Asthma / complications
  • Asthma / drug therapy
  • Electrocardiography
  • Female
  • Heart Arrest / chemically induced
  • Heart Arrest / physiopathology
  • Humans
  • Long QT Syndrome / pathology
  • Long QT Syndrome / physiopathology*
  • Metaproterenol / pharmacology

Substances

  • Adrenergic beta-Agonists
  • Metaproterenol
  • Albuterol