[Significance of adhesion molecules in oncology]

Pathologe. 1997 Mar;18(2):117-23. doi: 10.1007/s002920050199.
[Article in German]

Abstract

Cell-Cell-and cell-extracellular matrix interactions are important in the process of tumor cell invasion and metastasis. These interactions are mediated by adhesion molecules e.g. CD44, integrins, E-cadherin and N-CAM. The role of adhesion molecules along metastatic cascade as well as their importance in tumor differentiation and progression are discussed herein.

Publication types

  • Review

MeSH terms

  • Animals
  • Biomarkers, Tumor / analysis*
  • Cadherins / analysis
  • Cadherins / physiology
  • Cell Adhesion Molecules / analysis*
  • Cell Adhesion Molecules / physiology
  • Cell Movement / physiology
  • Humans
  • Hyaluronan Receptors / analysis
  • Hyaluronan Receptors / physiology
  • Integrins / analysis
  • Integrins / physiology
  • Neoplasm Invasiveness
  • Neoplasm Metastasis
  • Neoplasms / pathology*
  • Neoplasms / physiopathology
  • Neural Cell Adhesion Molecules / analysis
  • Neural Cell Adhesion Molecules / physiology

Substances

  • Biomarkers, Tumor
  • Cadherins
  • Cell Adhesion Molecules
  • Hyaluronan Receptors
  • Integrins
  • Neural Cell Adhesion Molecules