Efficacy of immune plasma in treatment of Argentine haemorrhagic fever and association between treatment and a late neurological syndrome

Lancet. 1979 Dec 8;2(8154):1216-7. doi: 10.1016/s0140-6736(79)92335-3.

Abstract

In a double-blind trial patients with Argentine haemorrhagic fever treated with immune plasma within 8 days of the onset of the disease had a much lower mortality than those given normal plasma. Some patients treated with immune plasma developed late neurological complications.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Blood Donors
  • Cerebellar Diseases / etiology
  • Clinical Trials as Topic
  • Double-Blind Method
  • Hemorrhagic Fever, American / mortality
  • Hemorrhagic Fever, American / therapy*
  • Humans
  • Immunization, Passive* / adverse effects
  • Neurologic Manifestations*
  • Retrospective Studies
  • Time Factors