Abstract
At present, bone histomorphometry remains the gold standard for the diagnosis of the various types of renal bone disease. In the search for a non-invasive method of diagnosis, biochemical serum markers of bone remodelling, in addition to serum intact parathyroid hormone and aluminium determinations, have been proposed as the most reliable tools and are at present widely used in clinical practice. Their respective diagnostic values, as separate items and in combined analysis, are thoroughly discussed in the present review.
MeSH terms
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Aluminum / blood
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Biomarkers / blood
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Bone Diseases / blood
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Bone Diseases / complications*
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Bone Diseases / diagnosis*
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Bone Diseases, Metabolic / blood
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Bone Diseases, Metabolic / etiology
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Bone Remodeling / physiology
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Calcinosis / blood
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Calcinosis / etiology
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Fibrous Dysplasia of Bone / diagnosis
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Humans
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Hypercalcemia / blood
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Hypercalcemia / etiology
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Kidney Diseases / blood
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Kidney Diseases / complications*
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Kidney Diseases / diagnosis*
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Osteomalacia / diagnosis
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Parathyroid Hormone / blood
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Phosphates / blood
Substances
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Biomarkers
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Parathyroid Hormone
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Phosphates
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Aluminum