Central nervous system involvement as a relapse of disseminated histoplasmosis in an Italian AIDS patient

J Infect. 1997 Jul;35(1):83-4. doi: 10.1016/s0163-4453(97)91169-5.

Abstract

A case of an Italian AIDS patient who developed both meningitis and cerebral mass lesion as a final relapse of disseminated histoplasmosis is reported. Central nervous system (CNS) involvement occurred while the patient was receiving both amphotericin B and itraconazole as maintenance therapy, thus indicating the difficulty of eradicating histoplasmosis in patients with AIDS.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / cerebrospinal fluid
  • AIDS-Related Opportunistic Infections / complications*
  • AIDS-Related Opportunistic Infections / drug therapy
  • Adult
  • Amphotericin B / therapeutic use
  • Antifungal Agents / therapeutic use
  • Fatal Outcome
  • Histoplasma*
  • Histoplasmosis / cerebrospinal fluid
  • Histoplasmosis / chemically induced*
  • Histoplasmosis / drug therapy
  • Humans
  • Italy
  • Itraconazole / therapeutic use
  • Male
  • Meningitis / drug therapy
  • Meningitis / microbiology*

Substances

  • Antifungal Agents
  • Itraconazole
  • Amphotericin B