Carbamazepine-phenprocoumon interaction

Eur Neurol. 1997;38(2):132-3. doi: 10.1159/000113178.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anticoagulants / adverse effects*
  • Anticoagulants / pharmacokinetics
  • Anticoagulants / therapeutic use
  • Anticonvulsants / adverse effects*
  • Anticonvulsants / pharmacokinetics
  • Anticonvulsants / therapeutic use
  • Carbamazepine / adverse effects*
  • Carbamazepine / pharmacokinetics
  • Carbamazepine / therapeutic use
  • Cerebral Infarction / blood
  • Cerebral Infarction / drug therapy*
  • Cytochrome P-450 CYP3A
  • Cytochrome P-450 Enzyme System / blood
  • Dose-Response Relationship, Drug
  • Drug Synergism
  • Enzyme Activation / drug effects
  • Epilepsy / blood
  • Epilepsy / drug therapy*
  • Humans
  • Liver / enzymology
  • Male
  • Mixed Function Oxygenases / blood
  • Phenprocoumon / adverse effects*
  • Phenprocoumon / pharmacokinetics
  • Phenprocoumon / therapeutic use
  • Prothrombin Time

Substances

  • Anticoagulants
  • Anticonvulsants
  • Carbamazepine
  • Cytochrome P-450 Enzyme System
  • Mixed Function Oxygenases
  • CYP3A protein, human
  • Cytochrome P-450 CYP3A
  • Phenprocoumon