Bromism: intoxication from a rare anticonvulsant therapy

Pediatr Emerg Care. 1997 Aug;13(4):268-70.

Abstract

Bromide, the first effective therapy for epilepsy, is not commonly prescribed today but has been advocated by some pediatric neurologists for the treatment of intractable seizures in children. We report a 17-year-old female patient with intractable epilepsy who insidiously developed bromism while on treatment with triple bromide elixir. We review the clinical presentation, diagnosis, pathophysiology, and management of bromism.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anticonvulsants / adverse effects*
  • Bromides / adverse effects*
  • Confusion / chemically induced
  • Epilepsy / drug therapy
  • Female
  • Humans
  • Irritable Mood / drug effects
  • Poisoning / therapy
  • Speech Disorders / chemically induced

Substances

  • Anticonvulsants
  • Bromides