This article presents an integrative model for understanding the range of individual differences arising from the bereavement process which occurs through the loss of a significant person, such as a spouse, parent or child. It is suggested that cognitive behavioral models are useful in determining stress reactions to bereavement; however, such models have certain limitations for adaptation purposes. Finally, to enhance well-being, reactions to loss are examined from a clinical perspective by using a five-phase model which outlines holistic adaptation processes, intervention strategies, and time span indicators.