[Neoadjuvant CYVADIC (cyclophosphamide, vincristine, adriamycin and dacarbazine) therapy for retroperitoneal leiomyosarcoma: a case report]

Hinyokika Kiyo. 1997 Aug;43(8):577-80.
[Article in Japanese]

Abstract

Retroperitoneal leiomyosarcoma is often too large to be completely removed. We report a 67-year-old woman successfully treated with neoadjuvant CYVADIC (cyclosphosphamide, vincristine, adriamycin and dacarbazine). The tumor was removed with the right kidney and ureter and a part of the vena cava after 2 courses of CYVADIC. The tumor recurred at the duodenum 7 years later and was completely removed following neoadjuvant CYVADIC. Neoadjuvant chemotherapy could be helpful for the complete resection of advanced leiomyosarcoma.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Chemotherapy, Adjuvant
  • Cyclophosphamide / administration & dosage
  • Dacarbazine / administration & dosage
  • Doxorubicin / administration & dosage
  • Female
  • Humans
  • Leiomyosarcoma / drug therapy*
  • Leiomyosarcoma / surgery
  • Retroperitoneal Neoplasms / drug therapy*
  • Retroperitoneal Neoplasms / surgery
  • Vincristine / administration & dosage

Substances

  • Vincristine
  • Dacarbazine
  • Doxorubicin
  • Cyclophosphamide

Supplementary concepts

  • CYVADIC protocol