Life events and disability in rheumatoid arthritis: a European cohort

Br J Rheumatol. 1997 Oct;36(10):1106-12. doi: 10.1093/rheumatology/36.10.1106.

Abstract

The objective was to study the relationship between life events (LE) and the clinical status of patients suffering from recently diagnosed rheumatoid arthritis (RA) in a 2 yr follow-up. As part of a multicentre European cohort study, 370 French and Dutch patients were questioned three times at 1 yr intervals about LE which had occurred in the previous year. Three criteria were used to quantify the degree of disease activity (Ritchie's index), the level of functional disability [Health Assessment Questionnaire (HAQ)] and perceived health [Overall Evaluation of Health (OEH)]. Total LE and desirable LE showed a weak negative correlation with the HAQ scores. On the other hand, death-related LE did not seem to modify patient status. The higher the number of health-associated LE, the greater the deterioration in HAQ and OEH scores. The results indicate that LE do not affect the course of early RA in a spectacular manner.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Arthritis, Rheumatoid / epidemiology
  • Arthritis, Rheumatoid / physiopathology*
  • Arthritis, Rheumatoid / therapy
  • Cohort Studies
  • Disability Evaluation*
  • Female
  • France / epidemiology
  • Humans
  • Life Change Events*
  • Male
  • Middle Aged
  • Netherlands / epidemiology
  • Prospective Studies
  • Quality of Life
  • Severity of Illness Index
  • Social Support
  • Surveys and Questionnaires
  • Time Factors