Conductivity detection in capillary electrophoresis--a powerful tool in ion analysis

J Capillary Electrophor. 1996 Jan-Feb;3(1):1-11.

Abstract

Conductivity detection in CE has recently become available in a commercial CE instrument. The new conductivity cell is based on an end-capillary concept. The conductivity sensor and the detection end of the fused-silica capillary are permanently encapsulated in two individually modified coupling connectors (ConTip, ConCap [both from Orion Research, Boston, MA, U.S.A.]). This open-architecture cell permits interchangeability of sensors and capillaries, while maintaining a precisely defined detection volume between those two components when inserted into the detector cell block. The detector's performance is evaluated for sensitivity, linearity, and reproducibility using low-mobility electrolytes. Electropherograms comprising a variety of ionic class separations including inorganic and organic anions, organic surfactants, alkali metals, alkaline earths, transition metals, and organic amines are shown along with separations of actual samples.

Publication types

  • Comparative Study

MeSH terms

  • Cations / analysis*
  • Electric Conductivity*
  • Electrochemistry / instrumentation
  • Electrochemistry / methods
  • Electrophoresis, Capillary / instrumentation
  • Electrophoresis, Capillary / methods*
  • Indicators and Reagents
  • Metals / analysis*
  • Sensitivity and Specificity
  • Spectrophotometry, Ultraviolet / methods
  • Vitamins / analysis*

Substances

  • Cations
  • Indicators and Reagents
  • Metals
  • Vitamins