Reliability of dipole localization for the movement-evoked field component MEF I

Int J Neurosci. 1997 Sep;91(1-2):123-32. doi: 10.3109/00207459708986370.

Abstract

The movement-evoked field I (MEF I) component is the largest and most stable neuromagnetic component accompanying self-paced movements. In order to use MEG for studying dynamic changes in the cortical organization of movements, data about the reliability and variability of these neuromagnetic components for individual subjects must be established during different sessions. For this aim, three male subjects were requested to perform self-paced flexions of their index finger and thumb in repeated sessions while the MEG was recorded by a 31 channel system. The MEF I was identified for each session and a single equivalent dipole was calculated for this component. The dipole localizations of the various sessions were compared. The standard deviation of the localization for all persons and all values amounts to 4.0-5.2 mm for the three spatial dimensions. Our data suggest that the spatial distance between two single focal sources fitted to the MEF I must be greater than 14 mm to be interpreted as distinct. However, the neuromagnetic field structure and the resulting dipole localization of the MEF I component are quite stable and could be used for the evaluation of cortical plasticity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Brain / anatomy & histology
  • Brain / physiology*
  • Finger Joint / physiology
  • Humans
  • Magnetic Resonance Imaging
  • Magnetoencephalography*
  • Male
  • Movement / physiology*
  • Neuronal Plasticity / physiology
  • Reproducibility of Results