Endocrine mucin-producing sweat gland carcinoma: a cutaneous neoplasm analogous to solid papillary carcinoma of breast

Am J Surg Pathol. 1997 Dec;21(12):1501-6. doi: 10.1097/00000478-199712000-00014.

Abstract

We describe two cases of a distinctive in situ and invasive cutaneous adnexal neoplasm occurring in the eyelid. Mucinous carcinoma represented the invasive portion of the tumor in one case, whereas the other infiltrated in small solid nests. The in situ component is identical to the recently described solid papillary carcinoma of the breast (endocrine ductal carcinoma in situ). Both tumors produced intra- and extracellular mucin, exhibited endocrine differentiation by immunohistochemistry and ultrastructural analysis, and were positive for estrogen and progesterone receptors.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Adenocarcinoma, Mucinous / pathology*
  • Adenocarcinoma, Mucinous / surgery
  • Aged
  • Breast Neoplasms / pathology*
  • Carcinoma, Papillary / pathology*
  • Eyelid Neoplasms / pathology*
  • Eyelid Neoplasms / surgery
  • Female
  • Humans
  • Middle Aged
  • Mucins / analysis
  • Mucins / biosynthesis*
  • Neoplasm Recurrence, Local
  • Sweat Gland Neoplasms / pathology*
  • Sweat Gland Neoplasms / surgery

Substances

  • Mucins