Association of CTLA-4 gene A-G polymorphism (IDDM12 locus) with acute-onset and insulin-depleted IDDM as well as autoimmune thyroid disease (Graves' disease and Hashimoto's thyroiditis) in the Japanese population

Diabetes. 1998 Jan;47(1):128-9. doi: 10.2337/diab.47.1.128.

Authors

T Awata¹, S Kurihara, M Iitaka, S Takei, I Inoue, C Ishii, K Negishi, T Izumida, Y Yoshida, R Hagura, N Kuzuya, Y Kanazawa, S Katayama

Affiliation

¹ The Fourth Department of Internal Medicine, Saitama Medical School, Japan. [email protected]

PMID: 9421386
DOI: 10.2337/diab.47.1.128

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Abatacept
Adolescent
Adult
Aged
Alleles
Antigens, CD
Antigens, Differentiation / genetics*
Antigens, Differentiation / physiology
CTLA-4 Antigen
Child
Child, Preschool
Diabetes Mellitus, Type 1 / epidemiology
Diabetes Mellitus, Type 1 / genetics*
Diabetes Mellitus, Type 1 / physiopathology
Gene Frequency
Genes / genetics*
Genotype
Graves Disease / epidemiology
Graves Disease / genetics*
Graves Disease / physiopathology
Humans
Immunoconjugates*
Infant
Japan / epidemiology
Middle Aged
Polymerase Chain Reaction
Polymorphism, Genetic
Thyroiditis, Autoimmune / epidemiology
Thyroiditis, Autoimmune / genetics*
Thyroiditis, Autoimmune / physiopathology

Substances

Antigens, CD
Antigens, Differentiation
CTLA-4 Antigen
CTLA4 protein, human
Immunoconjugates
Abatacept