A re-analysis of a randomized clinical trial for gastric cancer using interval censoring

Jpn J Clin Oncol. 1997 Dec;27(6):445-6. doi: 10.1093/jjco/27.6.445.

Abstract

In a previous randomized clinical trial against curatively resected gastric cancer, we compared the effect of immunochemotherapy to chemotherapy and obtained significantly better survival and disease-free survival time (DFS) in a combined therapy group. Although DFS was analysed with a conventional approach in which the onset of relapse was defined as the diagnosis of relapse, we considered it necessary to re-analyse the data and compare the results of an interval-censored approach with the conventional approach, in order to examine whether the conclusion might be altered depending on the approach.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Disease-Free Survival
  • Humans
  • Meta-Analysis as Topic*
  • Randomized Controlled Trials as Topic
  • Stomach Neoplasms* / mortality
  • Stomach Neoplasms* / surgery
  • Survival Rate