Abstract
Strains of Neisseria meningitidis of serogroup B isolated in the Czech Republic frequently belong to serotype 22. We analyzed the genetic relationships among strains of this serotype by using the multilocus enzyme electrophoresis technique and the polymorphism of the pilA gene. Our results indicate that these strains correspond to a highly heterogeneous population rather than to the expansion of a single clone.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alleles
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Bacterial Proteins / genetics*
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Czech Republic / epidemiology
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DNA, Bacterial / analysis*
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DNA, Bacterial / genetics
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DNA-Binding Proteins / genetics*
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Fimbriae Proteins*
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Humans
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Isoenzymes / genetics*
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Meningococcal Infections / epidemiology
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Meningococcal Infections / genetics*
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Meningococcal Infections / immunology
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Neisseria meningitidis / enzymology
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Neisseria meningitidis / genetics*
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Neisseria meningitidis / immunology
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Phylogeny
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Polymerase Chain Reaction
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Polymorphism, Genetic
Substances
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Bacterial Proteins
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DNA, Bacterial
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DNA-Binding Proteins
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Isoenzymes
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Fimbriae Proteins