Abstract
Setting out from the high prevalence of iatrogenic toxic effects on the liver and biliary system, the authors examine the pathophysiological mechanisms underlying and suggest an updated classification. The clinical models of the action of main drugs responsible are discussed.
MeSH terms
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Chemical and Drug Induced Liver Injury / etiology*
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Chemical and Drug Induced Liver Injury / prevention & control
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Common Bile Duct / drug effects*
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Dose-Response Relationship, Drug
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Drug-Related Side Effects and Adverse Reactions*
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Humans
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Liver / drug effects*