The Minnesota Multiphasic Personality Inventory (MMPI) was administered to 53 male inpatients of alcohol dependence syndrome (ICD-10) at the time of their admission to the Alcoholism Rehabilitation Program (ARP) of Shiga Mental Health Center Hospital and again at the time of their discharge. The pretreatment profile had high peaks above 60 on the scale F, Hs, D, Hy, Pd, Pa, Pt, Sc and MAS. The 20 scales in the 27 examined scales changed significantly after the 84 days' treatment in the direction of reduced symptoms (Table 3). The changes in scores between pre and post treatment objectively showed that the ARP was effective as the treatment of alcoholism. It might be the base of all the recovery that the subjects regained their intelligence through the sobriety. Their changes in scores failed to predict their prognoses.