The working activities of operators in the workstations along the italian motor ways involve repetitive movements of upper limbs and neck with asymmetric postures of the trunk. The tasks examined are characterized by factors potentially dangerous for developing musculo-skeletal disorders, such as repetitivity, and prolonged constrained postures. It is therefore crucial that dimensional and structural characteristics of the workplace are adequately designed, with regard to the anthropometric parameters and the type of activity performed. The results of our "on-site" investigation, using an observational method (OCRA), dedicated computerized modules for postural analysis (software "Vision 3000", Promatek, Ltd.), and recordings of myoelectrical activity (surface EMG) in the muscles of the shoulder girdle, have shown the need of a partial re-designing of the man-workstation system under investigation.