The discovery of LY293111, a novel, potent and orally active leukotriene B4 receptor antagonist of the biphenylphenol class

Adv Exp Med Biol. 1997:400A:381-6. doi: 10.1007/978-1-4615-5325-0_51.
No abstract available

MeSH terms

  • Administration, Oral
  • Animals
  • Benzoates* / administration & dosage
  • Benzoates* / pharmacology*
  • Bronchoconstriction / drug effects
  • Cell Membrane / metabolism
  • Guinea Pigs
  • Humans
  • Leukotriene B4 / pharmacology
  • Lung / physiology*
  • Neutrophils / drug effects
  • Neutrophils / physiology*
  • Phenols / pharmacology*
  • Receptors, Leukotriene B4 / antagonists & inhibitors
  • Receptors, Leukotriene B4 / metabolism*
  • Structure-Activity Relationship

Substances

  • Benzoates
  • LY 293111
  • Phenols
  • Receptors, Leukotriene B4
  • Leukotriene B4