Low intensities and 1.3 ratio produce distortion product otoacoustic emissions which are larger in heterozygous (+/dn) than homozygous (+/+) mice

Hear Res. 1998 Mar;117(1-2):24-30. doi: 10.1016/s0378-5955(98)00005-7.

Abstract

The f2/f1 frequency ratio of 1.3 in combination with stimulus levels of L1/L2 = 50/60 and 50/50 dB SPL produced a higher level of distortion product otoacoustic emissions (DPOAE) in the heterozygous (+/dn) mice than in the homozygous (+/+) mice. These results suggest that the dn gene carriers have a unique cochlear trait which may be related to the dn gene locus and expressed via a frequency- and intensity-dependent DPOAE function.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acoustic Stimulation
  • Animals
  • Deafness / genetics
  • Disease Models, Animal
  • Female
  • Heterozygote*
  • Homozygote*
  • Male
  • Mice
  • Otoacoustic Emissions, Spontaneous / genetics*
  • Phenotype