Abstract
The structure of an unusual dienone-phenol rearrangement product 4 obtained during the synthesis of mometasone furoate (Sch 32088) was assigned on the basis of NMR and x-ray crystallographic data. The mechanism of formation is discussed.
MeSH terms
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Anti-Inflammatory Agents / chemical synthesis*
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Anti-Inflammatory Agents / chemistry
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Crystallography, X-Ray
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Mometasone Furoate
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Phenols / chemistry*
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Pregnadienediols / chemical synthesis*
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Pregnadienediols / chemistry
Substances
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Anti-Inflammatory Agents
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Phenols
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Pregnadienediols
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Mometasone Furoate