[A case report: inhaled nitric oxide improves respiratory function in an infant with pulmonary hypertension]

Masui. 1998 Mar;47(3):300-5.
[Article in Japanese]

Abstract

Nitric oxide (NO) was administered to an infant in a near fatal crisis of pulmonary hypertension after total correction of double outlet right ventricle. Inhaled NO of 4 parts per million reduced pulmonary arterial pressure (PAP) and increased tidal volume during pressure limit ventilation. Both respiratory system compliance and resistance were improved with NO inhalation. There was a significant negative correlation between mean PAP and respiratory system compliance. We speculated that a reduction in PAP with NO inhalation resulted in the improvement of respiratory function. He was successfully weaned from mechanical ventilation.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Double Outlet Right Ventricle / surgery
  • Humans
  • Hypertension, Pulmonary / physiopathology
  • Hypertension, Pulmonary / therapy*
  • Infant
  • Male
  • Nitric Oxide / administration & dosage*
  • Postoperative Complications / physiopathology
  • Postoperative Complications / therapy*
  • Respiration*
  • Respiratory Therapy*

Substances

  • Nitric Oxide