[Development of tumor selection based on pathological stage in clinically localized prostate carcinoma]

Urologe A. 1998 Mar;37(2):195-8. doi: 10.1007/s001200050173.
[Article in German]

Abstract

Four hundred and eighty-eight radical retropubic prostatectomies (RRP) were performed on clinically localized prostate cancer at one institution within 5 years (1992-1996). These were then analyzed regarding the migration of pathological tumor stages towards more localized stages. Within the observation period, the annual rate of RRP increased by 81% from 69 to 125 cases. The authors noted a decline in the occurrence of advanced tumor stages (65.0% to 39.2%) and small cancers (< 0.5 cc: 7.2% to 1.6%) and an increase in pathological T2 tumors (30.4% to 55.2%). The rate of positive surgical margins declined from 34.7% to 12.8% (for all pathological stages). These data confirm trends which were observed in the USA with increasing detection and treatment of localized prostate cancer.

Publication types

  • English Abstract

MeSH terms

  • Biomarkers, Tumor / blood
  • Humans
  • Male
  • Mass Screening
  • Neoplasm Invasiveness
  • Neoplasm Staging
  • Prostate / pathology
  • Prostate-Specific Antigen / blood
  • Prostatectomy
  • Prostatic Neoplasms / pathology*
  • Prostatic Neoplasms / prevention & control
  • Prostatic Neoplasms / surgery

Substances

  • Biomarkers, Tumor
  • Prostate-Specific Antigen