A frequency and correlation analysis of motor deficits in Parkinson patients

Disabil Rehabil. 1998 Apr;20(4):142-50. doi: 10.3109/09638289809166074.

Abstract

Purpose: The present study explored the frequency and pattern of functional motor problems of a group of Parkinson patients, as a first step towards developing a rational approach to rehabilitation intervention addressing the primary symptoms of the disease.

Method: Sixty patients, consisting of 40% women and 60% men with a mean age of 63.5 years and of which 88% were taking L-dopa, underwent a number of standardized clinical tests including part III of the UPDRS. They were also interviewed about the frequency of motor problems occurring at home.

Results: Loss of trunk rotation as expressed in rolling in supine and reduced arm swing were the most frequently registered motor disorders (73%, 75%). Freezing at the start of, or during, walking was not observed during clinical testing but was frequently claimed to occur at home (48%, 23%). A broad spectrum of deficits regarding gait, posture, transfers and distal motor problems formed a cluster, which was strongly correlated with bradykinesia (p < 0.001). Principal component analysis identified four distinct problem areas: (1) axial motor performance; (2) akinetic gait problems; (3) rigidity; and (4) tremor.

Conclusions: Parkinson patients, particularly in the later stages of the disease, presented with significant levels of functional disability which was mainly linked with the underlying impairment of bradykinesia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Amantadine / therapeutic use
  • Antiparkinson Agents / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Humans
  • Incidence
  • Levodopa / therapeutic use
  • Male
  • Middle Aged
  • Movement
  • Parkinson Disease / drug therapy
  • Parkinson Disease / physiopathology
  • Parkinson Disease / rehabilitation*
  • Prognosis
  • Psychomotor Disorders / classification*
  • Psychomotor Disorders / epidemiology*
  • Psychomotor Disorders / physiopathology
  • Psychomotor Performance
  • Selegiline / therapeutic use
  • Sensitivity and Specificity
  • Severity of Illness Index
  • Surveys and Questionnaires
  • Time Factors

Substances

  • Antiparkinson Agents
  • Selegiline
  • Levodopa
  • Amantadine