Discrete chiasma formation models and their associated high order interference

J Math Biol. 1998 Apr;36(5):448-68. doi: 10.1007/s002850050108.

Abstract

We introduce some special chiasma formation processes. First a family of discrete chiasma formation processes is introduced and we determine the nature of higher order interference associated with those processes. Secondly we consider a two-stage chiasma formation process, where the associated recombination frequency between two markers depends not only on their map distance but also on their location along the chromosomes. We characterise under this process, in some cases, the nature of interference between two segments.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Chromosome Mapping
  • Crossing Over, Genetic
  • Genetic Linkage
  • Genetic Markers
  • Models, Genetic*
  • Models, Theoretical*
  • Recombination, Genetic*

Substances

  • Genetic Markers