Six kinds of facial nerve injury in 136 facial nerves of 68 rabbits were studied by quantitative pathology. The ratio of intrafascicular axon crossing and the ratio of intrafascicular area can reflect the extent of the lesions for non-cut injury (exposure, compression, stretch and crush) effectively. However, the ratio of mesial to distal intrafascicular area should be combined for the evaluation of cut injury (division and anastomosis). The mean optical density (F1), axon area (F13), and homogeneous degree (F49) can reflect quantitatively the form and extent of the single axon lesion and its content. The morphologic parameter (F10) can reflect the change of axon morphology. The results of quantitative pathologic study support the histopathologic study, and provide additional knowledge about the progress of serial axon lesions.