Cryptococcal meningitis and intracranial tuberculoma in a patient with Waldenstrom's macroglobulinemia treated with fludarabine

Leuk Lymphoma. 1998 Feb;28(5-6):617-20. doi: 10.3109/10428199809058373.

Abstract

We report a patient with Waldenstrom's Macroglobulinemia who presented with cryptococcal meningitis followed by an intracranial tuberculoma during the 18 months period after termination of cytotoxic therapy with Fludarabine. Opportunistic infections due to intracellular organisms are extremely rare in the course of this malignancy and we review the predisposing factors of these infectious entities.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / therapeutic use*
  • Brain Diseases / etiology
  • Brain Diseases / microbiology
  • Female
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use*
  • Meningitis, Cryptococcal / etiology*
  • Middle Aged
  • Opportunistic Infections / etiology*
  • Opportunistic Infections / microbiology
  • Tuberculoma / etiology*
  • Vidarabine / adverse effects
  • Vidarabine / analogs & derivatives*
  • Vidarabine / therapeutic use
  • Waldenstrom Macroglobulinemia / complications*
  • Waldenstrom Macroglobulinemia / drug therapy*

Substances

  • Antineoplastic Agents
  • Immunosuppressive Agents
  • Vidarabine
  • fludarabine