Abstract
In this study we evaluated the role of systemic chemotherapy in 23 previously untreated patients with brain metastases from both non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). In NSCLC group, 2 patients out of 14 had a brain response after treatment (1 complete and 1 partial response). In the group of 9 patients with SCLC, we observed 5 brain responses (3 complete and 2 partial responses). Brain responses were in accordance with extracranial responses although this appeared more clearly in SCLC than in NSCLC patients.
Publication types
-
Clinical Trial
-
Controlled Clinical Trial
MeSH terms
-
Adult
-
Aged
-
Antineoplastic Agents, Phytogenic / adverse effects
-
Antineoplastic Agents, Phytogenic / therapeutic use*
-
Antineoplastic Combined Chemotherapy Protocols / adverse effects
-
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
-
Brain Neoplasms / drug therapy*
-
Brain Neoplasms / secondary
-
Carcinoma, Non-Small-Cell Lung / drug therapy*
-
Carcinoma, Non-Small-Cell Lung / secondary
-
Carcinoma, Small Cell / drug therapy*
-
Carcinoma, Small Cell / secondary
-
Female
-
Humans
-
Lung Neoplasms / drug therapy*
-
Lung Neoplasms / pathology
-
Male
-
Middle Aged
-
Paclitaxel / adverse effects
-
Paclitaxel / therapeutic use*
-
Tomography, X-Ray Computed
-
Treatment Outcome
Substances
-
Antineoplastic Agents, Phytogenic
-
Paclitaxel