Eosinophilic fasciitis complicated with peripheral polyneuropathy

Intern Med. 1998 Apr;37(4):417-20. doi: 10.2169/internalmedicine.37.417.

Abstract

Peripheral polyneuropathy and the complication of eosinophilic fasciitis (EF) is rare; only 2 such cases have been described previously. A 40-year-old woman suffered from swelling of the extremities after strenuous exercise and complained of bilateral paresthesia on the soles of her feet. The diagnosis was EF according to clinical symptoms, peripheral eosinophilia, and histological examination of the fascia. Nerve conduction tests also revealed sensory disturbance as mononeuritis multiplex. After administration of prednisolone, the swelling and tenderness of the extremities improved immediately but the neuropathy lasted for 6 months.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biopsy
  • Eosinophilia / complications*
  • Eosinophilia / diagnosis
  • Eosinophilia / drug therapy
  • Fascia / pathology
  • Fasciitis / complications*
  • Fasciitis / diagnosis
  • Fasciitis / drug therapy
  • Female
  • Follow-Up Studies
  • Glucocorticoids / therapeutic use
  • Humans
  • Magnetic Resonance Imaging
  • Neural Conduction
  • Peripheral Nervous System Diseases / drug therapy
  • Peripheral Nervous System Diseases / etiology*
  • Peripheral Nervous System Diseases / physiopathology
  • Prednisolone / therapeutic use

Substances

  • Glucocorticoids
  • Prednisolone