Suicide with moclobemide and perazine

Int J Legal Med. 1998;111(4):196-8. doi: 10.1007/s004140050149.

Abstract

A 51-year-old woman who was diagnosed as suffering from depression was found dead in her flat. The autopsy revealed no morphological changes sufficient to explain death. Toxicological analysis was performed and the drugs moclobemide (49.9 mg/l), perazine (1.27 mg/l) and some metabolites were identified in the blood. A combined drug intoxication resulting in synergistic effects to cardiovascular disorders was proposed as the cause of death.

Publication types

  • Case Reports

MeSH terms

  • Antipsychotic Agents / pharmacokinetics
  • Antipsychotic Agents / poisoning*
  • Autopsy / methods*
  • Benzamides / pharmacokinetics
  • Benzamides / poisoning*
  • Drug Synergism
  • Female
  • Humans
  • Middle Aged
  • Moclobemide
  • Monoamine Oxidase Inhibitors / pharmacokinetics
  • Monoamine Oxidase Inhibitors / poisoning*
  • Perazine / pharmacokinetics
  • Perazine / poisoning*
  • Suicide*

Substances

  • Antipsychotic Agents
  • Benzamides
  • Monoamine Oxidase Inhibitors
  • Perazine
  • Moclobemide