[Localization of the gene for 4 hereditary multiple exostoses families]

Y Tang; J H Xia; J N Zhou; H J Li; D P Wang; H P Dai; Z G Long; B S Tang; L Huang; H X Deng

[Localization of the gene for 4 hereditary multiple exostoses families]

Yi Chuan Xue Bao. 1998;25(1):1-7.

[Article in Chinese]

Authors

Y Tang¹, J H Xia, J N Zhou, H J Li, D P Wang, H P Dai, Z G Long, B S Tang, L Huang, H X Deng

Affiliation

¹ National Laboratory of Medical Genetics of P. R. China, Changsha.

PMID: 9648398

Abstract

We investigated 11 families with hereditary multiple exostoses (EXT) by linkage analysis using 8 short-tandem-repeat (CA)n polymorphic markers on chromosomes 8, 11 and 19. The Lod score in four families indicated that the gene responsible for EXT is located in the pericentromeric region of chromosome 11.

Publication types

English Abstract

MeSH terms

Chromosome Mapping*
Chromosomes, Human, Pair 11*
Exostoses, Multiple Hereditary / genetics*
Female
Genetic Linkage
Humans
Male
Polymerase Chain Reaction