Abstract
Insulin-like growth factor 1 (IGF-1) is the final pathway of the growth hormone cascade, and is a better clinical measure of acromegaly than growth hormone itself. In patients with acromegaly, medical treatment with a somatostatin analog normalizes growth hormone and IGF-1 levels and produces clinical improvement quickly.
MeSH terms
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Acromegaly / diagnosis*
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Acromegaly / physiopathology
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Acromegaly / therapy*
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Adult
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Biomarkers
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Female
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Growth Hormone / metabolism
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Hormone Antagonists / therapeutic use
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Humans
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Insulin-Like Growth Factor I / metabolism
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Male
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Middle Aged
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Somatostatin / analogs & derivatives
Substances
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Biomarkers
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Hormone Antagonists
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Somatostatin
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Insulin-Like Growth Factor I
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Growth Hormone