The authors have an experience in diagnosis and treatment of pulmonary embolism in 194 patients. Much attention is paid to diagnosis of thrombosis of the deep veins, phlebography and duplex scanning as the most informative methods. Due to regular unspecific and specific prophylaxis of deep phlebothrombosis in operated patients, pulmonary artery embolism occurred only in 2 patients for 12 years. Valid diagnosis of pulmonary artery embolism is thought possible only in application by pulmonary scanning and angiopulmonography. Mostly conservative method of treatment was used, only in 2 patients successful embolectomy was performed. Anticoagulation (heparin) and fibrinolytic (streptase) therapy was carried out. The results of streptase administration were superior to those of heparin injections. Recovery rate after fibrinolytic therapy made up 86.4%.