Abstract
Acute renal allograft rejection is suspected by the clinician when the serum creatinine value increases in a patient for no other particular cause. A renal allograft biopsy may confirm the diagnosis. This report describes 2 patients with stable serum creatinine; however, protocol biopsy showed acute rejection changes according to the Banff criteria. No anti-rejection treatment was started and their graft function remained stable for 6 months. These two cases focus on the fact that renal allograft rejection should first of all be regarded as a clinical diagnosis which could be substantiated by histological findings.
MeSH terms
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Acute Disease
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Anti-Inflammatory Agents / administration & dosage
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Anti-Inflammatory Agents / therapeutic use
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Biopsy
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Creatinine / blood
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Follow-Up Studies
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Glucocorticoids / administration & dosage
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Glucocorticoids / therapeutic use
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Graft Rejection / blood
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Graft Rejection / diagnosis
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Graft Rejection / drug therapy
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Graft Rejection / pathology*
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Humans
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Immunosuppressive Agents / administration & dosage
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Immunosuppressive Agents / therapeutic use
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Kidney Transplantation / pathology*
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Kidney Tubules / pathology
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Leukocytes, Mononuclear / pathology
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Living Donors
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Lymphocytes / pathology
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Male
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Methylprednisolone / administration & dosage
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Methylprednisolone / therapeutic use
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Middle Aged
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Transplantation, Homologous
Substances
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Anti-Inflammatory Agents
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Glucocorticoids
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Immunosuppressive Agents
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Creatinine
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Methylprednisolone