Use of an oral antiseptic bioadhesive tablet in dogs

J Vet Dent. 1995 Sep;12(3):87-91.

Abstract

V3703 (Stomadhex) is a tablet with bioadhesive properties enabling it to remain in place for several hours after it has been placed on the oral mucosa. It continuously releases chlorhexidine and niacinamide. In a study conducted in 15 dogs, the tablets were well tolerated by the animals. The product significantly reduced (p < 0.05): dental plaque; quantitative periodontopathogen and total anaerobic bacterial counts; spirochetes; and halitosis when used daily over a 14 day period. Gingivitis was also reduced, though not significantly (p = 0.07). Stomadhex treatment can provide a carry-over effect following dental scaling by reducing oral microflora and retarding the reappearance of dental plaque.

MeSH terms

  • Administration, Topical
  • Analysis of Variance
  • Animals
  • Anti-Infective Agents, Local / administration & dosage*
  • Bacteria, Anaerobic / drug effects
  • Chlorhexidine / administration & dosage*
  • Colony Count, Microbial
  • Dental Plaque / drug therapy
  • Dental Plaque / microbiology
  • Dental Plaque / veterinary*
  • Dog Diseases / drug therapy*
  • Dog Diseases / microbiology
  • Dogs
  • Drug Combinations
  • Gingivitis / drug therapy
  • Gingivitis / veterinary
  • Halitosis / drug therapy
  • Halitosis / veterinary*
  • Linear Models
  • Mouth Mucosa
  • Niacinamide / administration & dosage*
  • Spirochaetales / drug effects
  • Tablets

Substances

  • Anti-Infective Agents, Local
  • Drug Combinations
  • Tablets
  • Niacinamide
  • Chlorhexidine