Objective: To analyze the effect of a previous donor oocyte cycle on the outcome of subsequent attempts.
Design: Retrospective study.
Setting: Oocyte donation program at The New York Hospital/Cornell Medical Center.
Patient(s): Two hundred sixty-seven patients undergoing 354 fresh cycles of oocyte donation.
Intervention(s): None.
Main outcome measure(s): Clinical outcomes were divided into groups based on the attempt number of each cycle for each patient. Results were calculated for each recipient cycle.
Result(s): A clinical pregnancy rate of 56.2% and ongoing pregnancy/delivery rate per retrieval of 50.3% were noted. No statistically significant differences in clinical outcomes were found between the first, second, and third attempts. A significant increase was noted in the ongoing pregnancy/delivery rate per recipient cycle for the second attempt in those patients who had a delivery after the first attempt compared with those who did not.
Conclusion(s): We demonstrated an overall clinical pregnancy rate of 56.2% and an ongoing pregnancy/delivery rate of 50.3% per retrieval. Outcome for the second attempt was associated with success or failure during an initial attempt at oocyte donation.