The antioxidant N-acetylcysteine does not delay disease onset and death in a transgenic mouse model of amyotrophic lateral sclerosis

Ann Neurol. 1998 Aug;44(2):293. doi: 10.1002/ana.410440229.
No abstract available

Publication types

  • Letter

MeSH terms

  • Acetylcysteine / blood
  • Acetylcysteine / pharmacology
  • Acetylcysteine / therapeutic use*
  • Administration, Oral
  • Amyotrophic Lateral Sclerosis / drug therapy*
  • Amyotrophic Lateral Sclerosis / genetics
  • Animals
  • Body Weight / drug effects
  • Disease Progression
  • Free Radical Scavengers / blood
  • Free Radical Scavengers / pharmacology
  • Free Radical Scavengers / therapeutic use*
  • Half-Life
  • Mice
  • Mice, Transgenic
  • Point Mutation / drug effects
  • Vitamin E / pharmacology

Substances

  • Free Radical Scavengers
  • Vitamin E
  • Acetylcysteine