Abstract
We investigated the expression of different cell adhesion molecules on cord blood (CB) and bone marrow (BM) CD34+/CD38+ and CD34+/CD38- cells. CD11a and CD62L were more expressed in CB than in BM CD34+/CD38- subset, suggesting a possible advantage in homing and engraftment. A short exposure to various cytokines increased CD62L expression only in the more differentiated CB and BM CD34+/CD38+ cells.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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ADP-ribosyl Cyclase
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ADP-ribosyl Cyclase 1
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Antigens, CD*
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Antigens, CD34 / analysis
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Antigens, Differentiation / analysis
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Bone Marrow Cells / chemistry
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Bone Marrow Cells / cytology*
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Cell Adhesion Molecules / analysis*
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Fetal Blood / chemistry
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Fetal Blood / cytology*
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Flow Cytometry
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Hematopoietic Stem Cells / chemistry*
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Humans
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L-Selectin / analysis
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Lymphocyte Function-Associated Antigen-1 / analysis
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Membrane Glycoproteins
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NAD+ Nucleosidase / analysis
Substances
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Antigens, CD
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Antigens, CD34
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Antigens, Differentiation
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Cell Adhesion Molecules
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Lymphocyte Function-Associated Antigen-1
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Membrane Glycoproteins
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L-Selectin
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ADP-ribosyl Cyclase
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CD38 protein, human
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NAD+ Nucleosidase
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ADP-ribosyl Cyclase 1